The No. 12 Wake Forest Demon Deacons (9-1, 6-1 in ACC) face off with the Clemson Tigers (7-3, 5-2) in an ACC Atlantic game at Memorial Stadium with the kickoff scheduled for noon E.T. Below, we look at the Wake Forest vs. Clemson odds and lines, and make our expert college football picks, predictions and bets.
Rankings courtesy of the AFCA Coaches Poll powered by USA TODAY Sports.
Wake Forest bounced back from its first loss of the season to beat the NC State Wolfpack 45-42 as 1-point road favorites in Week 11. The Demon Deacons are 5-5 ATS and 5-5 O/U with the 68th-toughest schedule, according to USA TODAY’s Jeff Sagarin.
Clemson won its third straight game by pummeling the UConn Huskies 44-7 but failed to cover as 41-point home favorites. This will be the first Clemson team to not make the College Football Playoff since 2014.
The Tigers are 2-8 ATS and 3-6-1 O/U with the 51st-ranked strength of schedule, according to Sagarin.
Clemson thrashed Wake Forest 37-13 as 34-point favorites last season but the Tigers obviously lost a lot of pieces including former QB Trevor Lawrence.
However, Demon Deacons QB Sam Hartman played in last year’s Clemson-Wake Forest game. Hartman completed 11-of-21 passes for 182 yards.